Fig. 10

Histopathological image of colon tissues of Sf-BGV/TX100 (immunized with S. flexneri bacterial ghost vaccine produced by TX100 and challenged with S. flexneri 2b serotype “ATCC 12022”). (a, b, and c) demonstrate intact morphological features of the colonic wall, as well as an integral submucosal layer (star) with intact glandular elements and limited evidence of inflammatory cell infiltrates. Numerous goblet cell recordings (arrows) were seen in the intestinal crypts