Table 1 Baseline characteristics according to endoscopic bile reflux grading
From: Effect of bile reflux on gastric juice microbiota in patients with different histology phenotypes
Parameters | Grade 0 (n = 19) | Grade 1 (n = 22) | Grade 2 (n = 9) | P-value |
|---|---|---|---|---|
Age, yrs. median (range) | 68.0 (27–82) | 67.5 (42–81) | 62.0 (24–85) | 0.663 |
Male, n (%) | 10 (52.6) | 17 (77.3) | 7 (77.8) | 0.189 |
Hypertension, n (%) | 3 (15.8) | 4 (18.2) | 3 (33.3) | 0.534 |
Diabetes, n (%) | 3 (15.8) | 3 (13.6) | 3 (33.3) | 0.411 |
H. pylori infections, n (%) | 5 (26.3) | 13 (59.1) | 5 (55.6) | 0.090 |
Background histologic manifestation of atrophic gastritis with intestinal metaplasia, n (%) | 13 (68.4) | 19 (86.4) | 7 (77.8) | 0.384 |
pH of gastric juice, median (interquartile range), among 36 patients | 3.1 (1.7–6.9) among 15 patients | 6.8 (5.9–7.2) among 16 patients | 7.2 (6.6–7.4) among 5 patients | 0.062 |
Main histologic phenotypes, n (%) | 0.100 | |||
No neoplasm | 7 (36.8) | 2 (9.1) | 1 (11.1) | |
Low-grade dysplasia | 6 (31.6) | 9 (40.9) | 6 (66.7) | |
Early gastric cancer | 6 (31.6) | 11 (50.0) | 2 (22.2) |