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Fig. 5 | Gut Pathogens

Fig. 5

From: The C-terminal proline-rich repeats of Enteropathogenic E. coli effector EspF are sufficient for the depletion of tight junction membrane proteins and interactions with early and recycling endosomes

Fig. 5

Schematic diagram showing the effect of EspF-PRR domains on tight junction membrane proteins. EspF may be recruited to the plasma membrane through its interaction with SNX9. Once at the plasma membrane, the PRR domains of EspF likely interact and activate markers of early and recycling endosomes to mediate the displacement of claudin-1, claudin-4 and occludin from the tight junctions into the cytoplasm and their depletion

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Gut Pathogens

ISSN: 1757-4749