Fig. 1

Disease alterations in gut alpha diversity show clearly opposing patterns at the microbiome and mycobiome levels. Comparison of Shannon Index and Pielou Evenness Index for gut microbiomes and the gut mycobiomes of the three subject groups (namely Controls, CD and ITB) at the taxonomic levels of OTU/ASV, Species and Genus. Pairwise comparisons between the different groups are denoted by bars between corresponding boxes with the associated corrected p values (FDR) given in the notation: @ 0.05 < FDR < =0.1; * 0.01 < FDR < =0.05; ** 0.001 < FDR < =0.01, *** FDR < =0.001