Fig. 2

ITB and CD indicate distinct patterns of microbiome- and mycobiome-level alterations with respect to the control group. A Principal Coordinate Analysis (PCoA) plots showing the variations of the Species-level Gut Microbiome profiles and Gut Mycobiome profiles of individuals belonging to the Control, ITB and CD groups. The PCoAs were performed using the weighted Jaccard distance measure. Species-level PCoAs obtained for the Kendall distance measure have been shown in Supplementary Figure 1. Similar plots for the other taxonomic levels using other distance measures are provided in Supplementary Figures 2, 3, 4, and 5. B Boxplot comparing the first species-level PCoA Axes obtained for the gut microbiome and mycobiome profiles obtained using the three different measures. Pairwise comparisons between the different groups are denoted by bars between corresponding boxes with the associated corrected p values (FDR) given in the notation: @ 0.05 < FDR < =0.1; * 0.01 < FDR < =0.05; ** 0.001 < FDR < =0.01, *** FDR < =0.001