Table 1 Localization of virulence and heavy metal resistance genes across chromosomes and plasmids of different replicon types and mobilities in the pandrug-resistant K. pneumoniae isolates

KP3

Chromosome

–

mrkABCDFHIJ, fimABCDEFGHIK entABCDEFS, fyuA, irp1, ybtAEPQSTUX, iroE, iroN

silR

pEGY_KP3^a

IncHI1B/IncFIB

Conjugative

iutA, iucABCD, rmpA

terWXY

Plasmid KP3-1

IncL/M

Conjugative

–

–

Plasmid KP3-2

ColRNAI

Non-mobilizable

–

–

Plasmid KP3-3

ColRNAI

Mobilizable

–

–

KP8

Chromosome

–

–

mrkABCDFHIJ, fimABCDEFGHIK, entABCDEFS, iroE, iroN

silR

pEGY_KP8^a

IncHI1B/IncFIB

Conjugative

iutA, iucABCD

terABCDEWXYZ

Plasmid KP8-1

IncL/M

Conjugative

–

–

Plasmid KP8-2

IncFIB/IncFII_K

Conjugative

–

–

Plasmid KP8-3

ColRNAI

Non-mobilizable

–

–

Plasmid KP8-4

ColRNAI

Mobilizable

–

–

KP11

Chromosome

–

–

mrkABCDFHIJ, fimABCDEFGHIK, entABCDEFS, iroE, iroN, iutA, kfuAB

silR

pEGY_KP11^a

IncHI1B/IncFIB

Conjugative

iucABCD, iutA

terABCDEWXYZ

Plasmid KP11-1

IncFIB

Non-mobilizable

–

–

Plasmid KP11-2

IncFIB_K/IncFII_K

Conjugative

–

arsABCDR, merCPRT, pcoABCDERS, silABCEFGPRS

Plasmid KP11-3

ColRNAI

Mobilizable

–

–

KP20

Chromosome

–

–

mrkABCDFHIJ, fimABCDEFGHIK, entABCDEFS, fyuA, irp1, irp2, ybtAEPQSTUX, iroE, iroN, iutA

silA, silR

pEGY_KP20^a

IncHI1B/IncFIB

Conjugative

iucABCD, iutA

terABCDEWXYZ

Plasmid KP20-1

IncL/M

Conjugative

–

–

Plasmid KP20-2

IncFIB/IncFII_K

Conjugative

–

–

Plasmid KP20-3

IncFIB

Non-mobilizable

–

–

Plasmid KP20-4

ColRNAI

Non-mobilizable

–

–

KP22

Chromosome

–

–

mrkABCDFHIJ, fimABCDEFGHIK, entABCDEFS fyuA, irp1, irp2, ybtAEPQSTUX, iroE, iroN, iutA

silA, silR

pEGY_KP22^a

IncHI1B/IncFIB

Conjugative

iucABCD, iutA

terABCDEWXYZ

Plasmid KP22-1

IncL/M

Conjugative

–

–

Plasmid KP22-2

IncFIB/IncFII_K

Conjugative

–

–

Plasmid KP22-3

ColRNAI

Non-mobilizable

–

–

Plasmid KP22-4

IncFIB

Non-mobilizable

–

–

Plasmid KP22-5

Col(BS512)

Non-mobilizable

–

–