Fecal microbiome alterations of mice following immunization with gold nanoparticle vaccines against enterohemorrhagic Escherichia coli

Table 1 Significant differentially abundant families pre- and post-immunization

Group	Family	p-value	I or D From Pre-Vaccination
EscC	Bifidobacteriaceae	0.015152	D
	Clostridiaceae	0.004329	D
	Eubacterium_coprostanoligenes_group	0.025974	I
	Lachnospiraceae	0.025974	D
	Oscillospiraceae	0.008658	D
Eae	Butyricicoccaceae	0.015152	D
	Clostridiaceae	0.002165	D
	Eggerthellaceae	0.041126	I
	Erysipelatoclostridiaceae	0.002165	I
	Monoglobaceae	0.004329	I
	Rikenellaceae	0.002165	I
EscC + Eae	Clostridiaceae	0.008658	D
Adj	Acholeplasmataceae	0.025974	I
	Anaerovoracaceae	0.015152	I
	Bifidobacteriaceae	0.015152	I
	Defluviitaleaceae	0.062771	I
	Eggerthellaceae	0.008658	I
	Muribaculaceae	0.041126	I
	Peptostreptococcaceae	0.041126	D

I, increased in post-immunization compared with pre-vaccination; D, decreased in post-immunization compared with pre-vaccination. Significance was evaluated with t-test

ISSN: 1757-4749