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Table 2 Relevant predictors and risk factors associated with detection of pathogens 

From: Impact of invasive infections on clinical outcomes in acute pancreatitis: early predictive factors and implications for prophylactic anti-infective therapy

Variable

Univariable Analysis

Multivariable Analysis

r2

p value

Coefficients

t

p value

B

Std. Error

95% CI

Bacterial contamination

Sex

0.016

0.0782

-

-

-

-

-

Age [years]

0.010

0.1675

-

-

-

-

-

BMI [kg/m2]

0.001

0.7547

-

-

-

-

-

Moderate pancreatitis *

0.002

0.4903

-

-

-

-

-

Severe pancreatitis *

0.007

0.2553

-

-

-

-

-

Post-ERCP

0.002

0.5664

-

-

-

-

-

WBC [giga/l] onset

0.052

0.0013

0.015

0.006

0.004-0.027

2.636

0.0091

WBC [giga/l] day 1

0.035

0.0093

-

-

-

-

-

CRP [mg/l]

onset

0.019

0.0521

-

-

-

-

-

CRP [mg/l]

day 1

0.024

0.0315

-

-

-

-

-

Creatinine [mg/dl] onset

0.007

0.2342

-

-

-

-

-

Creatinine [mg/dl] day 1

0.015

0.0909

-

-

-

-

-

Lipase [U/l]

onset

0.000

0.8943

-

-

-

-

-

Lipase [U/l] day 1

0.001

0.7141

-

-

-

-

-

Amylase [U/l] onset

0.000

0.8753

-

-

-

-

-

Amylase [U/l] day 1

0.000

0.8085

-

-

-

-

-

Biliary Etiology

0.002

0.4916

-

-

-

-

-

Pleural effusion

0.054

0.0010

0.086

0.077

-0.066-0.238

1.116

0.2657

Ascitic fluid

0.070

0.0002

0.198

0.077

0.047-0.349

2.589

0.0104

Volume therapy (first 24 h)

0.007

0.2511

-

-

-

-

-

Volume therapy (24–48 h)

0.005

0.3370

-

-

-

-

-

Volume therapy (after 48 h)

0.008

0.2370

-

-

-

-

-

  1. Simple linear regression was used for univariable analysis and multiple linear regression for multivariable analysis to evaluate relevant early predictors and risk factors associated with bacterial load and consecutively worse clinical outcome. Variables with Spearman’s r² > 0.05 and p < 0.01 in univariable analysis were considered as relevant for inclusion into multivariable analysis. BMI = Body mass index; ERCP = Endoscopic retrograde cholangiopancreatography; WBC = White blood cell count; CRP = C-reactive protein 
  2. * In accordance with the revised Atlanta classification of 2012 [2