Skip to main content

Table 4 Meta-regression comparing Clostridioides difficile asymptomatic carrier prevalence of specific populations versus healthy group

From: Heterogeneity of Clostridioides difficile asymptomatic colonization prevalence: a systematic review and meta-analysis

Population characteristics (n)

Coefficient

95% CI

p value

Inferior

Superior

Healthy population (n = 6)

Reference

Cystic Fibrosis (n = 2)

0.47

0.25

0.68

<0.001

Outbreak (n = 3)

0.30

0.13

0.48

<0.001

Cancer population (n = 6)

0.23

0.09

0.37

0.001

Hospital setting – patients at admission (n = 10)

0.17

0.05

0.30

0.006

Hospital setting – hospitalized patients (n = 6)

0.15

0.02

0.29

0.029

Long-term care facilities/Elderly population (n = 13)

0.15

0.03

0.27

0.017

Intensive Care Unit (n = 7)

0.14

0.003

0.28

0.046

Hospital setting – health care workers (n = 2)

0.11

-0.09

0.32

0.272

Cirrhosis (n = 1)

0.33

0.08

0.59

0.011

Kidney transplant (n = 1)

0.30

0.03

0.56

0.029

Inflammatory bowel disease (n = 1)

0.10

-0.18

0.37

0.481

*Another setting (n = 4)

-0.005

-0.16

0.15

0.953

  1. Meta-regression was performed with the healthy population as the reference group. Model R2 = 31%; test of moderators: (QM = 37, p < 0.001). *Two studies of veterinarians or community individuals with close contact with small companion animals, one with patients attending their general practitioners and one with patients presenting at the emergency departments, are included