Fig. 11

Heatmaps illustrating the correlation matrices associated with disease immunopathology, highlighting the relationships between the different parameters analyzed. C57BL/6 mice, infected or not with T. gondii and treated or not with SGE 30 µg during the acute and chronic phases. Correlation matrices were calculated using R Studio software, employing the Spearman test for non-parametric samples and the Pearson test for parametric samples. Heatmaps were then generated using the "corrplot" package. Correlations are represented by colors: red indicates negative correlations and blue indicates positive correlations, with color intensity reflecting the strength of the correlation. The categories analyzed are: A infected and untreated animals in the acute phase; B infected animals treated with SGE 30 µg in the acute phase; C infected and untreated animals in the chronic phase; and D infected animals treated with SGE 30 µg in the chronic phase