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Table 7 Diagnostic performance of ELISA for H. pylori IgG detection in Saliva compared to Serum

From: Sero—salivary detection of H. pylori immunoglobulins and parasitic infection among healthcare individuals suffering from gastrointestinal disorders with correlation to personal hygiene

IgG

Serum

k

Sensitivity

Specificity

PPV

NPV

Accuracy

AUC

95% C.I

Cut off#

Negative

(n = 187)

Positive

(n = 13)

No. (%)

No. (%)

Saliva

 Negative

186 (99.5%)

1 (7.7%)

0.918

92.3

99.5

92.3

99.5

99.0

0.960

0.881 – 1.000

 > 5

 Positive

1 (0.5%)

12 (92.3%)

 χ2 (FEp)

168.445* (< 0.001*)

         
  1. PPV Positive predictive value, NPV Negative predictive value, AUC Area Under a Curve, CI Confidence Intervals
  2. χ2 Chi square test, k Cohen’s Kappa coefficient
  3. p: p value for association between different categories
  4. *: Statistically significant at p ≤ 0.05
  5. #Cut off was choose according to Youden index
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Gut Pathogens

ISSN: 1757-4749