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Table 1 Baseline characteristics of patients and healthy volunteers

From: Coupling culturomics and metagenomics sequencing to characterize the gut microbiome of patients with cancer treated with immune checkpoint inhibitors

NSCLC

N = 11

Age

 Median

64 (52–73)

Sex

 Male

9 (69%)

ECOG performance-status score

 0

8 (61%)

 1

4 (31%)

 2

1 (8%)

Histology

 Adenocarcinoma

9 (69%)

 Squamous

4 (31%)

PDL-1 expresssion

  > 50%

11 (85%)

  ≤ 50%

2 (15%)

Treatment

 Anti-PD-L1

10 (77%)

 Anti-PD-L1 + chemo

2 (15%)

 Anti-PD-L1 + Anti CTLA-4 + chemo

1 (8%)

Melanoma

N = 9

Age

 Median

61 (45–81)

Sex

 Male

6 (67%)

ECOG performance-status score

 0

5 (56%)

 1

3 (33%)

 2

1 (11%)

Cancer Type

 Cutaneous

8 (89%)

 Uveal

1 (11%)

BRAF

 Wild Type

7 (78%)

 Mutant

1 (11%)

 Unknown

1 (11%)

Treatement

 Anti-PD-L1

3 (33%)

 Anti-PD-L1 + Anti CTLA-4

6 (67%)

Healthy volunteers (HV)

N=7

Age

 

 Median

37 (27–42)

Sex

 

 Male

3 (43%)